Contributed software

Tool Description References
i-cisTarget An integrative genomics method for the prediction of regulatory features (motifs and in vivo features), and cis-regulatory modules in Drosophila

Manuscript in preparation
cisTargetX Predict motifs and target genes in Drosophila, starting from a list of co-expressed genes.

[1]
TOUCAN Workbench for regulatory sequence analysis. Features include: detection of conserved sequences, motif discovery (MotifSampler, Oligo-analysis), motif matching (MotifLocator, MotifScanner), statistical over-representation, module discovery (ModuleSearcher), module matching (ModuleScanner), etc.
Launch Toucan (Java Web Start application)

[2][3]
ENDEAVOUR / HIGHFLY ENDEAVOUR/HIGHFLY Framework for the computational prioritisation of genes by genomic data fusion, based on the similarity with a set of training genes. This similarity takes into account: scientific literature (MEDLINE abstracts), Gene Ontology, KEGG pathways, InterPro domains, BIND protein interactions, EST-based expression data, microarray gene expression data, transcription factor binding sites, cis-regulatory modules, and BLAST-based sequence similarity.
Credits: Leo-Charles Tranchevent and Bert Coessens

[4][5][6]
ModuleSearcher and ModuleMiner Solve the combinatorial optimization problem to find the optimal combination of transcription factor binding sites in a set of co-regulated sequences. ModuleSearcher and ModuleScanner are available within TOUCAN. ModuleMiner is an extension of ModuleSearcher that increases CRM and target gene specificity by performing genome-wide optimizations.
Credits: Peter Van Loo
[7][8][9]
 
 



Bioinformatics resource lists

Name Link Description
EMBOSS http://10.33.126.32/emboss-explorer/ Local installation of the EMBOSS suite of bioinformatics tools (only accessible within the KULeuven firewall).
Note: you can also use the standalone EMBOSS package on our linux server (request a user account).
Mobyle http://mobyle.pasteur.fr/cgi-bin/portal.py
 
 
Links directories Directories of links to various bioinformatics tools and web services