TOUCAN

Launch now

Click here to launch the Java Web Start Application

Description

TOUCAN is a workbench for regulatory sequence analysis on metazoan genomes : comparative genomics, detection of significant transcription factor binding sites, and detection of cis-regulatory modules (combinations of binding sites) in sets of coexpressed/coregulated genes. It is a platform independent, standalone Java application that is tightly linked with Ensembl, and was built using the BioJava package.SOAP web services are used to remotely access multiple algorithms for comparative genomics, motif detection, and module detection.

References

• Stein Aerts, Gert Thijs, Bert Coessens, Mik Staes, Yves Moreau, Bart De Moor (2003) ``TOUCAN : Deciphering the Cis-Regulatory Logic of Coregulated Genes''. Nucl Acids Res, vol. 31, no. 6, 2003, pp. 1753-1764.
• Stein Aerts, Peter Van Loo, Gert Thijs, Herbert Mayer, Rainer de Martin, Yves Moreau and Bart De Moor (2005) "TOUCAN 2: the all-inclusive open source workbench for regulatory sequence analysis". Nucl Acids Res, vol. 33 (Web Server issue), W393-6.